Middle Deschutes is at the tail end of big salmon flies but far from over I’d guess.  Plenty of PED’s Pale Morning Duns, Caddis and even some BWO’s mixed in. 

Don’t forget attractors like Renegades and Purple Haze. 
Nymphs and Streamers are a good bet, all the same nymphs listed above for the Lower River and Hell Razor Leeches and Sculpzilla’s.